{"id":303,"date":"2025-12-26T22:15:14","date_gmt":"2025-12-26T13:15:14","guid":{"rendered":"https:\/\/junsei.or.jp\/blog\/?p=303"},"modified":"2026-01-08T01:03:06","modified_gmt":"2026-01-07T16:03:06","slug":"post-303","status":"publish","type":"post","link":"https:\/\/junsei.or.jp\/blog\/post-303\/","title":{"rendered":"\u8a8d\u77e5\u75c7\u4e88\u9632\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u30fb\u8a8d\u77e5\u75c7\u30ea\u30b9\u30af\u56e0\u5b50"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u9ad8\u9f62\u5316<\/strong>\u306b\u3068\u3082\u306a\u3044\u8a8d\u77e5\u75c7\u306f\u6025\u5897\u3057\u3066\u3044\u307e\u3059\u3002\u300c\u539a\u751f\u52b4\u50cd\u7701\u306e\u8a8d\u77e5\u75c7\u65bd\u7b56\u306e\u73fe\u72b6\u306b\u3064\u3044\u3066\u300d\u306b\u3088\u308c\u3070\u3001<strong><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color 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https:\/\/junsei.or.jp\/blog\/wp-content\/uploads\/2025\/12\/18392e289dcf360ea552e8df1098e475-400x292.jpeg 400w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u5c90\u961c\u85ac\u79d1\u5927\u5b66\u306e\u5831\u544a\u306b\u3088\u308c\u3070<strong>\u30d5\u30a7\u30eb\u30ac\u30fc\u30c9\u306f\u03b1\u30bb\u30af\u30ec\u30bf\u30fc\u30bc\u6d3b\u6027\u3092\u8a98\u5c0e\u3059\u308b<\/strong>\u3053\u3068\u304c\u5b9f\u8a3c\u3055\u308c\u3066\u304a\u308a\u3001\u30b0\u30ed\u30fc\u30d3\u30a2\u30df\u30a8\u30ea\u30f3\u7814\u7a76\u6240\u306e\u5831\u544a\u3067\u306f\u30d5\u30a7\u30eb\u30ac\u30fc\u30c9\uff08\u30d5\u30a7\u30eb\u30e9\u9178\u3001\u30ac\u30fc\u30c7\u30f3\u30a2\u30f3\u30bc\u30ea\u30ab\uff09\u6295\u4e0e\u306b\u3088\u308a\u03b1\u30bb\u30af\u30ec\u30bf\u30fc\u30bc\u767a\u73fe\u91cf\u304c\u6709\u610f\u306b\u5897\u52a0\u3059\u308b\u3053\u3068\u304c\u78ba\u8a8d\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u307e\u305f\u3001Acta Neuropathologica(29 July 2020)\u306e\u5831\u544a\u3067\u306f\u3001\u30a2\u30df\u30ed\u30a4\u30c9\u03b2\u6fc3\u5ea6\u306f\u751f\u7406\u5b66\u7684\u6a5f\u80fd\u3068\u75c5\u7406\u5b66\u7684\u6a5f\u80fd\u3092\u8abf\u7bc0\u3059\u308b\u305f\u3081\u306b\u91cd\u8981\u306a\u305f\u3081\u3001<strong>\u591a\u3059\u304e\u305f\u308a\u5c11\u306a\u3059\u304e\u305f\u308a\u3059\u308b\u3068\u6a5f\u80fd\u969c\u5bb3\u3092\u5f15\u304d\u8d77\u3053\u3057<\/strong>\u3001\u751f\u7406\u5b66\u7684\u306b\u6700\u9069\u306a\u6fc3\u5ea6\u304c\u5b58\u5728\u3057<strong><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color 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class=\"wp-block-paragraph\"><strong>\u30d5\u30a7\u30eb\u30e9\u9178<\/strong>\u306f\u3001\u30d5\u30ea\u30fc\u30e9\u30b8\u30ab\u30eb\u3001\u6162\u6027\u708e\u75c7\u3001\u03b2\u30bb\u30af\u30ec\u30bf\u30fc\u30bc\u306e\u8ee2\u5199\u3092\u6e1b\u5c11\u3055\u305b\u3001<strong>\u8133\u5185\u306e\u30a2\u30df\u30ed\u30a4\u30c9\u03b2\u306e\u6e1b\u5c11<\/strong>\u3068\u3001\u30a2\u30df\u30ed\u30a4\u30c9\u03b2\u306b\u3088\u308b\u795e\u7d4c\u7d30\u80de\u306e\u640d\u5931\u3092\u6e1b\u5c11\u3055\u305b\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<strong>\u30ac\u30fc\u30c7\u30f3\u30a2\u30f3\u30bc\u30ea\u30ab<\/strong>\u306b\u7279\u5fb4\u7684\u306b\u542b\u307e\u308c\u308b<strong>\u30ad\u30b5\u30f3\u30c8\u30c8\u30ad\u30b7\u30f3<\/strong>\u306f\u3001\u8a18\u61b6\u306b\u304b\u304b\u308f\u308b\u795e\u7d4c\u4f1d\u9054\u7269\u8cea\u306e1\u3064\u3067\u3042\u308b\u30a2\u30bb\u30c1\u30eb\u30b3\u30ea\u30f3\u3092\u5206\u89e3\u3059\u308b\u9175\u7d20\u306e\u30a2\u30bb\u30c1\u30eb\u30b3\u30ea\u30f3\u30a8\u30b9\u30c6\u30e9\u30fc\u30bc\u306e\u6709\u610f\u306a\u963b\u5bb3\u3092\u793a\u3057\u3001\u540c\u3058\u304f<strong>\u30c7\u30af\u30eb\u30b7\u30f3<\/strong>\u3082\u6d77\u99ac\u306b\u304a\u3051\u308b\u30a2\u30bb\u30c1\u30eb\u30b3\u30ea\u30f3\u30a8\u30b9\u30c6\u30e9\u30fc\u30bc\u6d3b\u6027\u3092\u963b\u5bb3\u3059\u308b\u3053\u3068\u3067\u6297\u5065\u5fd8\u4f5c\u7528\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u4fdd\u967a\u9069\u5fdc\u306e\u85ac\u5264<\/strong>\u306e\u3001<strong>\u30c9\u30cd\u30da\u30b8\u30eb<\/strong>\uff08\u30a2\u30ea\u30bb\u30d7\u30c8\uff09\u306f\u610f\u6b32\u4f4e\u4e0b\u306b\u3001<strong>\u30ac\u30e9\u30f3\u30bf\u30df\u30f3<\/strong>\uff08\u30ec\u30df\u30cb\u30fc\u30eb\uff09\u306f\u60c5\u7dd2\u4e0d\u5b89\u5b9a\u306b\u3001<strong>\u30ea\u30d0\u30b9\u30c1\u30b0\u30df\u30f3<\/strong>\uff08\u30a4\u30af\u30bb\u30ed\u30f3\/\u30ea\u30d0\u30b9\u30bf\u30c3\u30c1\uff09\u306f\u8cbc\u308a\u85ac\u3067\u56a5\u4e0b\u56f0\u96e3\u6642\u306b\u3001<strong>\u30e1\u30de\u30f3\u30c1\u30f3<\/strong>\uff08\u30e1\u30de\u30ea\u30fc\uff09\u306f\u8208\u596e\u3084\u5f98\u5f8a\u306b\u7528\u3044\u3089\u308c\u308b\u306a\u3069\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u3089\u306e\u4fdd\u967a\u9069\u5fdc\u85ac\u5264\u306f<strong>\u8a8d\u77e5\u75c7\u306e\u9032\u884c\u3092\u3084\u3084\u9045\u3089\u305b\u308b<\/strong>\u85ac\u5264\u3067\u3059\u3002<strong>\u30b3\u30ea\u30f3\u30a8\u30b9\u30c6\u30e9\u30fc\u30bc\u963b\u5bb3\u85ac<\/strong>\uff08\u30c9\u30cd\u30da\u30b8\u30eb\u3001\u30ea\u30d0\u30b9\u30c1\u30b0\u30df\u30f3\u3001\u30ac\u30e9\u30f3\u30bf\u30df\u30f3\uff09\u306e<strong>\u526f\u4f5c\u7528<\/strong>\u3068\u3057\u3066\u3001\u5410\u304d\u6c17\u30fb\u5614\u5410\u3084\u4e0b\u75e2\u3001<strong>\u98df\u6b32\u4e0d\u632f<\/strong>\u306a\u3069\u306e\u6d88\u5316\u5668\u75c7\u72b6\u3001\u982d\u75db\u3001\u8108\u304c\u9045\u304f\u306a\u308b\u5f90\u8108\u3084\u3001\u8108\u304c\u4e71\u308c\u308b\u4e0d\u6574\u8108\u3001<strong>\u6012\u308a\u3063\u307d\u304f\u306a\u3063\u305f\u308a\u3001\u653b\u6483\u7684\u306b\u306a\u3063\u305f\u308a<\/strong>\u3059\u308b\u306a\u3069\u304c\u5272\u3068\u591a\u304f\u307f\u3089\u308c\u307e\u3059\u3002<strong>\u30e1\u30de\u30f3\u30c1\u30f3<\/strong>\uff08\u30e1\u30de\u30ea\u30fc\uff09\u306e\u4e3b\u306a<strong>\u526f\u4f5c\u7528<\/strong>\u306b\u306f\u3001<strong>\u3081\u307e\u3044<\/strong>\u3001\u50be\u7720\u3001\u4fbf\u79d8\u3001\u8840\u5727\u4e0a\u6607\u3001\u5e7b\u899a\u306a\u3069\u304c\u3042\u308a\u307e\u3059\u3002\u7279\u306b\u9ad8\u9f62\u8005\u3067\u306f<strong>\u8ee2\u5012\u306e\u30ea\u30b9\u30af<\/strong>\u304c\u9ad8\u307e\u308b\u305f\u3081\u6ce8\u610f\u304c\u5fc5\u8981\u3067\u3059\u3002\u3053\u308c\u3089\u4fdd\u967a\u9069\u5fdc\u306e\u85ac\u5264\u3067\u3001\u526f\u4f5c\u7528\u306e\u7591\u3044\u304c\u3042\u308b\u5834\u5408\u306f\u4e3b\u6cbb\u533b\u306b\u76f8\u8ac7\u3057\u3066\u304f\u3060\u3055\u3044\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u30d5\u30a7\u30eb\u30ac\u30fc\u30c9\u306f\u3001\u8a8d\u77e5\u75c7\u306e\u4e88\u9632\u76ee\u7684\u3084MCI\uff08\u8efd\u5ea6\u8a8d\u77e5\u969c\u5bb3\uff09\u306e\u6bb5\u968e\u3067\u3042\u308c\u3070\u3001<strong>\u8a8d\u77e5\u75c7\u306e\u767a\u75c7\u3092\u9632\u6b62\u30fb\u56de\u5fa9\u3067\u304d\u308b<\/strong>\u3053\u3068\u3092\u65e5\u672c\u8a8d\u77e5\u75c7\u4e88\u9632\u5b66\u4f1a\u304c\u627f\u8a8d\u3057\u3066\u3044\u308b<strong>\u300c\u30e1\u30c7\u30a3\u30ab\u30eb\u30b5\u30d7\u30ea\u300d<\/strong>\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<figure class=\"wp-block-image alignfull size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"448\" height=\"600\" src=\"https:\/\/junsei.or.jp\/blog\/wp-content\/uploads\/2025\/12\/274ef424f3af7aa446fed5bf5d6e31c4-448x600.jpeg\" alt=\"\" class=\"wp-image-463\" srcset=\"https:\/\/junsei.or.jp\/blog\/wp-content\/uploads\/2025\/12\/274ef424f3af7aa446fed5bf5d6e31c4-448x600.jpeg 448w, https:\/\/junsei.or.jp\/blog\/wp-content\/uploads\/2025\/12\/274ef424f3af7aa446fed5bf5d6e31c4-224x300.jpeg 224w, https:\/\/junsei.or.jp\/blog\/wp-content\/uploads\/2025\/12\/274ef424f3af7aa446fed5bf5d6e31c4.jpeg 800w\" sizes=\"auto, (max-width: 448px) 100vw, 448px\" \/><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"554\" height=\"292\" src=\"https:\/\/junsei.or.jp\/blog\/wp-content\/uploads\/2025\/12\/c4e28ef0615c9586a5713124beb457d9.jpg\" alt=\"\" class=\"wp-image-466\" srcset=\"https:\/\/junsei.or.jp\/blog\/wp-content\/uploads\/2025\/12\/c4e28ef0615c9586a5713124beb457d9.jpg 554w, https:\/\/junsei.or.jp\/blog\/wp-content\/uploads\/2025\/12\/c4e28ef0615c9586a5713124beb457d9-400x211.jpg 400w\" sizes=\"auto, (max-width: 554px) 100vw, 554px\" \/><\/figure>\n<\/div>\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"441\" height=\"255\" src=\"https:\/\/junsei.or.jp\/blog\/wp-content\/uploads\/2025\/12\/9b518dbe58ecfd5be060dfd7a65cf0c0.jpg\" alt=\"\" class=\"wp-image-468\" style=\"aspect-ratio:1.729456461793002;width:508px;height:auto\" srcset=\"https:\/\/junsei.or.jp\/blog\/wp-content\/uploads\/2025\/12\/9b518dbe58ecfd5be060dfd7a65cf0c0.jpg 441w, https:\/\/junsei.or.jp\/blog\/wp-content\/uploads\/2025\/12\/9b518dbe58ecfd5be060dfd7a65cf0c0-400x231.jpg 400w\" sizes=\"auto, (max-width: 441px) 100vw, 441px\" \/><\/figure>\n<\/div>\n\n\n<p class=\"has-black-color has-text-color has-link-color wp-elements-9ac00cf961d1ea846fe5a532228b76c6 wp-block-paragraph\"><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u6a5f\u80fd\u6027\u8868\u793a\u98df\u54c1\u306e\u5236\u5ea6\u304c\u3067\u304d\u3066\u6ca2\u5c71\u306e\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u304c\u6ce8\u76ee\u3055\u308c\u3066\u3044\u307e\u3059\u304c\u3001\u30a8\u30d3\u30c7\u30f3\u30b9\u3082\u306f\u3063\u304d\u308a\u3057\u306a\u3044\u3082\u306e\u3082\u591a\u3044<\/strong>\u3067\u3059\u3002\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u306b\u3082\u4e16\u754c\u57fa\u6e96\u306e\u8a55\u4fa1\u304c\u5fc5\u8981\u3067\u3059\u3002\u30d5\u30a7\u30eb\u30ac\u30fc\u30c9100M\u306f\u3001\u7c73\u56fd\u306eJournal of Alzheimer&#8217;s Disease Reports\uff08DOI 10.3233\/ADR-200211\uff09\u3078\u63b2\u8f09\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u56fd\u5185\u3067\u306f\u3001<strong>\u65e5\u672c\u8133\u795e\u7d4c\u5916\u79d1\u5b66\u4f1a\u3001\u65e5\u672c\u795e\u7d4c\u5b66\u4f1a\u3001\u65e5\u672c\u8a8d\u77e5\u75c7\u4e88\u9632\u5b66\u4f1a 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class=\"wp-block-group alignfull\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-block-group-is-layout-constrained\">\n<figure class=\"wp-block-embed aligncenter is-type-video is-provider-youtube wp-block-embed-youtube wp-embed-aspect-16-9 wp-has-aspect-ratio\"><div class=\"wp-block-embed__wrapper\">\n<iframe loading=\"lazy\" title=\"\u65e5\u672c\u8a8d\u77e5\u75c7\u4e88\u9632\u5b66\u4f1a\u8a8d\u5b9a\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u2605\u30d5\u30a7\u30eb\u30ab\u3099\u30fc\u30c8\u3099\u00ae 100M\u7d39\u4ecb\u52d5\u753b\" width=\"1778\" height=\"1000\" src=\"https:\/\/www.youtube.com\/embed\/J6Oovq42qAk?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen><\/iframe>\n<\/div><figcaption 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class=\"wp-block-paragraph\"><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u2464<strong>\u300c\u30d7\u30e9\u30ba\u30de\u30ed\u30fc\u30b2\u30f3\u300d<\/strong>\u306b\u306f\u3001\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u578b\u8a8d\u77e5\u75c7\u306e\u8efd\u5ea6\u306a\u8a18\u61b6\u969c\u5bb3\u306e\u6539\u5584\u3001\u30d1\u30fc\u30ad\u30f3\u30bd\u30f3\u75c5\u306e\u975e\u904b\u52d5\u75c7\u72b6\u306e\u6539\u5584\u3001\u8a8d\u77e5\u6a5f\u80fd\u306e\u4e00\u90e8\uff08\u8a18\u61b6\u529b\u306a\u3069\uff09\u306e\u7dad\u6301\u3001\u305d\u3057\u3066\u5e7b\u899a\u75c7\u72b6\u3084\u7761\u7720\u969c\u5bb3\u306e\u6539\u5584\u3068\u3044\u3063\u305f\u30a8\u30d3\u30c7\u30f3\u30b9\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u30db\u30bf\u30c6\u7531\u6765\u30d7\u30e9\u30ba\u30de\u30ed\u30fc\u30b2\u30f3\u3092\u7528\u3044\u305f\u30b5\u30d7\u30ea\u3067\u3059\u3002 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class=\"wp-block-paragraph\">\u2465<strong>\u300c\u30ce\u30d3\u30ec\u30c1\u30f3\u300d<\/strong>\u3092\u542b\u3080\u30b5\u30d7\u30ea\u306b\u306f\u3001\u8a8d\u77e5\u6a5f\u80fd\u306e\u4e00\u90e8\u3084\u6392\u5c3f\u6a5f\u80fd\u306e\u6539\u5584\u306a\u3069\u306b\u3064\u3044\u3066\u300c\u30d2\u30c8\u81e8\u5e8a\u8a66\u9a13\u300d\u306b\u57fa\u3065\u3044\u305f\u30a8\u30d3\u30c7\u30f3\u30b9\u304c\u5b58\u5728\u3057\u307e\u3059\u3002&nbsp;\u6771\u5317\u5927\u5b66\u306a\u3069\u306e\u7814\u7a76\u6a5f\u95a2\u3067\u3001\u30ce\u30d3\u30ec\u30c1\u30f3\u304c<strong>\u8133\u306e\u795e\u7d4c\u7d30\u80de\u306e\u30cd\u30c3\u30c8\u30ef\u30fc\u30af\u3092\u6d3b\u6027\u5316<\/strong>\u3055\u305b\u308b\u50cd\u304d\u3092\u6301\u3064\u3053\u3068\u304c\u7814\u7a76\u3055\u308c\u3066\u304a\u308a\u3001\u9ad8\u9f62\u8005\u306e\u8a8d\u77e5\u6a5f\u80fd\u306e\u4f4e\u4e0b\u3092\u9045\u3089\u305b\u308b\u52b9\u679c\u304c\u78ba\u8a8d\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u30b5\u30d7\u30ea\u3092\u9078\u3076\u969b\u306f\u3001\u30d2\u30c8\u81e8\u5e8a\u8a66\u9a13\u30c7\u30fc\u30bf\u3084\u7814\u7a76\u7d50\u679c\u3092\u53c2\u8003\u306b\u3057\u3064\u3064\u3001\u4fe1\u983c\u3067\u304d\u308b\u30e1\u30fc\u30ab\u30fc\u306e\u88fd\u54c1\u3092\u9078\u3076<\/strong>\u3053\u3068\u304c\u5927\u5207\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u300c\u8a8d\u77e5\u75c7\u306e\u4e88\u9632\u3092\u4e3b\u5f35\u3059\u308b\u30b5\u30d7\u30ea\u306e\u591a\u304f\u306f\u30a8\u30d3\u30c7\u30f3\u30b9\u306b\u4e4f\u3057\u304f\u300d<\/strong>\u30a4\u30c1\u30e7\u30a6\u8449\u30a8\u30ad\u30b9\u3001\u30bb\u30b5\u30df\u30f3\u3001NMN\u3001\u30d9\u30fc\u30bf\u30ab\u30ed\u30c1\u30f3\u3001\u30ec\u30b9\u30d9\u30e9\u30c8\u30ed\u30fc\u30eb\u3001\u9577\u547d\u8349\u3001GABA\u3001\u305d\u3057\u3066\u30d5\u30a7\u30eb\u30ac\u30fc\u30c9\u985e\u4f3c\u54c1\u306e\u30d5\u30a7\u30eb\u30e9\u9178\u306a\u3069\u306f\u3001\u30d2\u30c8\u306e\u5927\u898f\u6a21\u81e8\u5e8a\u7814\u7a76\u3067\u4e88\u9632\u3084\u6539\u5584\u52b9\u679c\u306e\u5831\u544a\u306f\u5b58\u5728\u3057\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<p class=\"has-black-color has-text-color has-link-color wp-elements-fc72adf9ed7b8c50a5df4ba97f6f3adf wp-block-paragraph\">\u6ca2\u5c71\u306e\u30b5\u30d7\u30ea\u306e\u8cfc\u5165\u306f\u907f\u3051\u3066\u3001\u5148\u305a\u306f\u898f\u5247\u6b63\u3057\u3044\u7761\u7720\u3068\u98df\u4e8b\u3001\u904b\u52d5\u3092\u5927\u5207\u306b\u3057\u307e\u3057\u3087\u3046\u3002\u7279\u306b\u300c\u30b5\u30d7\u30ea\u306e\u8cb7\u3044\u904e\u304e\u8ca7\u4e4f\u300d\u306b\u306a\u3089\u306a\u3044\u3088\u3046\u306b\u6ce8\u610f\u3057\u307e\u3057\u3087\u3046\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><br><\/p>\n\n\n\n<h1 class=\"wp-block-heading\">\u8a8d\u77e5\u75c7\u306e\u30ea\u30b9\u30af\u56e0\u5b50\u306b\u3064\u3044\u3066<\/h1>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-vivid-red-color\">2024\u5e74\u7248 Lancet(\u4e16\u754c5\u5927\u533b\u5b66\u8a8c)<\/mark><\/strong>\u306b\u3088\u308b\u3068\u3001<strong><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-vivid-red-color\">\u8a8d\u77e5\u75c7\u306e\u30ea\u30b9\u30af\u56e0\u5b50<\/mark><\/strong>\u3068\u3057\u3066\u4ee5\u4e0b\u306e\u3082\u306e\u304c\u3042\u308b\u3068\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<h4 class=\"wp-block-heading\">\u3010\u65e9\u671f\u3011<strong>\u24605%\uff1a<mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-vivid-red-color\">\u6559\u80b2\u4e0d\u8db3<\/mark><\/strong><\/h4>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<h4 class=\"wp-block-heading\">\u3010\u4e2d\u5e74\u671f\u3011<strong>\u24617%\uff1a<mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-vivid-red-color\">\u96e3\u8074<\/mark>\u3001\u24627%\uff1a<mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-vivid-red-color\">\u9ad8LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u8840\u75c7<\/mark>\u3001\u24633%\uff1a<mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-vivid-red-color\">\u3046\u3064\u75c5<\/mark>\u3001\u24643%\uff1a<mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-vivid-red-color\">\u5916\u50b7\u6027\u8133\u640d\u50b7<\/mark>\u3001\u24652%\uff1a<mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-vivid-red-color\">\u8eab\u4f53\u4e0d\u6d3b\u52d5\uff08\u904b\u52d5\u4e0d\u8db3\uff09<\/mark>\u3001\u24662%\uff1a<mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-vivid-red-color\">\u7cd6\u5c3f\u75c5<\/mark>\u3001\u24672%\uff1a<mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-vivid-red-color\">\u55ab\u7159<\/mark>\u3001\u24682%\uff1a<mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-vivid-red-color\">\u9ad8\u8840\u5727<\/mark>\u3001\u24691%\uff1a<mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-vivid-red-color\">\u80a5\u6e80<\/mark>\u3001\u246a1%\uff1a<mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-vivid-red-color\">\u904e\u5ea6\u306e\u98f2\u9152<\/mark><\/strong><\/h4>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<h4 class=\"wp-block-heading\">\u3010\u8001\u5e74\u671f\u3011<strong>\u246b5%\uff1a<mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-vivid-red-color\">\u793e\u4f1a\u7684\u5b64\u7acb<\/mark>\u3001\u246c3%\uff1a<mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-vivid-red-color\">\u5927\u6c17\u6c5a\u67d3<\/mark>\u3001\u246d2%\uff1a<mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-vivid-red-color\">\u8996\u529b\u4f4e\u4e0b<\/mark><\/strong><\/h4>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">2024\u5e74\u7248\u306eLancet\u306b\u3088\u308c\u3070\u3001\u3053\u308c\u3089<strong><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-vivid-red-color\">\u2460\uff5e\u246d\u306e\u4fee\u6b63\u53ef\u80fd\u306a\u30ea\u30b9\u30af\u56e0\u5b50<\/mark><\/strong>\u306b\u5bfe\u5fdc\u3059\u308b\u3053\u3068\u3067\u3001<strong>\u8a8d\u77e5\u75c7\u306e<mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-vivid-red-color\">\u300c\u7d0445%\u306f\u4e88\u9632\u307e\u305f\u306f\u9045\u5ef6\u300d\u3067\u304d\u308b<\/mark><\/strong>\u53ef\u80fd\u6027\u304c\u9ad8\u3044\u3068\u5831\u544a\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"480\" height=\"320\" src=\"https:\/\/junsei.or.jp\/blog\/wp-content\/uploads\/2025\/12\/408bb821a8fe433493b9ee96980c65d2.jpg\" alt=\"\" class=\"wp-image-410\" style=\"width:508px;height:auto\" srcset=\"https:\/\/junsei.or.jp\/blog\/wp-content\/uploads\/2025\/12\/408bb821a8fe433493b9ee96980c65d2.jpg 480w, https:\/\/junsei.or.jp\/blog\/wp-content\/uploads\/2025\/12\/408bb821a8fe433493b9ee96980c65d2-400x267.jpg 400w\" sizes=\"auto, (max-width: 480px) 100vw, 480px\" \/><\/figure>\n<\/div>\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u8a8d\u77e5\u75c7\u306e\u8a98\u56e0\u3068\u306a\u308b\u7fd2\u6163<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u2460\u826f\u8cea\u306a\u7761\u7720\u6642\u9593\u306e\u4e0d\u8db3<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u7761\u7720\u304c5\u6642\u9593\u4ee5\u4e0b\u306e\u4eba<\/strong>\u306f\u3001<strong>\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u306e\u30ea\u30b9\u30af\u304c30%\u4e0a\u304c\u308b<\/strong>\u3053\u3068\u304c\u5224\u660e\u3057\u3066\u3044\u307e\u3059\u3002\u6df1\u7761\u7720\u306f\u3001\u8133\u304c\u30a2\u30df\u30ed\u30a4\u30c9\u03b2\u3092\u6392\u9664\u3059\u308b\u305f\u3081\u306b\u91cd\u8981\u306a\u6642\u9593\u3067\u3059\u3002\u7761\u7720\u306f\uff11\u65e5\uff16\u6642\u9593\u4ee5\u4e0a\u306f\u5fc5\u8981\u3067\u3059\u304c\u3001<strong>9\u6642\u9593\u4ee5\u4e0a\u3067\u3082\u8a8d\u77e5\u75c7\u30ea\u30b9\u30af<\/strong>\u306f\u4e0a\u304c\u308a\u307e\u3059\u3002<strong><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-vivid-red-color\">\u300c\u9069\u5207\u306a\u7761\u7720\u6642\u9593\u306f\u3001\u6210\u4eba\u30671\u65e56\u301c8\u6642\u9593\u300d<\/mark><\/strong>\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u2461\u6b6f\u306e\u624b\u5165\u308c\u3092\u3057\u306a\u3044<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u6771\u5317\u5927\u5927\u5b66\u9662\u306e\u7814\u7a76\u30b0\u30eb\u30fc\u30d7\u306b\u3088\u308b\u3068\u3001\u8133\u304c\u5065\u5eb7\u306a\u4eba\u306e\u6b6f\u306f\u5e73\u574714.9\u672c\u3067\u3057\u305f\u304c\u3001\u8a8d\u77e5\u75c7\u306e\u7591\u3044\u3042\u308a\u3068\u8a3a\u65ad\u3055\u308c\u305f\u65b9\u306f\u5e73\u57479.4\u672c\u3067\u3057\u305f\u3002<strong><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color 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style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-vivid-red-color\">\u300c3\u676f\u307e\u3067\u300d<\/mark><\/strong>\u306a\u3089\u8a8d\u77e5\u75c7\u306e\u30ea\u30b9\u30af\u3092\u4e0b\u3052\u307e\u3059\u3002<mark style=\"background-color: rgba(0, 0, 0, 0);\" class=\"has-inline-color has-vivid-red-color\"><b>\u30a2\u30eb\u30b3\u30fc\u30eb<\/b><\/mark>\u3067\u306f<strong><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-vivid-red-color\">\u300c11\uff47\u306e\u30a2\u30eb\u30b3\u30fc\u30eb\u307e\u3067\u300d<\/mark><\/strong>\u306a\u3089\u8a8d\u77e5\u75c7\u306e\u30ea\u30b9\u30af\u3092\u4e0b\u3052\u307e\u3059\u300210\uff47\u306e\u30a2\u30eb\u30b3\u30fc\u30eb\u306f\u65e5\u672c\u91520.5\u5408\u3001\u30a6\u30a4\u30b9\u30ad\u30fc\u30b7\u30f3\u30b0\u30eb1\u676f\u3001\u30d3\u30fc\u30eb350ml1\u672c\u30017\uff05\u7f36\u30c1\u30e5\u30fc\u30cf\u30a40.5\u7f36\u3001\u713c\u914e0.5\u5408\u3001\u30ef\u30a4\u30f30.5\u676f\u3068<strong><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-vivid-red-color\">\u7d50\u69cb\u5c11\u306a\u3081<\/mark><\/strong>\u3067\u3059\u3002<strong>25g\u4ee5\u4e0a\u306e\u30a2\u30eb\u30b3\u30fc\u30eb\u4f9d\u5b58\u3067\u306f\u3001\u8a8d\u77e5\u75c7\u306e\u30ea\u30b9\u30af\u304c\u9ad8\u307e\u308a<\/strong>\u307e\u3059\u3002<strong><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-vivid-red-color\">\u7dd1\u8336<\/mark>\u306f\uff11\u676f\u3054\u3068\u306b\u8a8d\u77e5\u75c7\u306e\u30ea\u30b9\u30af\u30926\uff05\u4e0b\u3052\u3066\u304f\u308c\u308b<\/strong>\u306e\u3067\u3001\u98f2\u3081\u3070\u98f2\u3080\u307b\u3069\u8a8d\u77e5\u75c7\u306e\u4e88\u9632\u306b\u3088\u3044\u3068\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3057\u304b\u3057\u3001\u6210\u4eba\u306e\u30ab\u30d5\u30a7\u30a4\u30f3\u6442\u53d6\u91cf\u306f400mg\u307e\u3067\u3068\u5b9a\u3081\u3089\u308c\u3066\u304a\u308a\u3001\u7dd1\u8336\u306a\u3089\u4e0a\u9650\u306f\uff11\u65e52,000ml \u672a\u6e80\u304c\u76ee\u5b89\u3067\u3059\u3002\u30ab\u30d5\u30a7\u30a4\u30f3\u306b\u3088\u308b\u5165\u7720\u969c\u5bb3\u3092\u9632\u3050\u305f\u3081\u306b\u3001\u8a8d\u77e5\u75c7\u4e88\u9632\u3068\u3057\u3066\u306f<strong><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-vivid-red-color\">\u300c\u7dd1\u8336\u306f\u5348\u524d\u3092\u4e2d\u5fc3\u306b\u3001\uff11\u65e5\u7d04500ml \u7a0b\u5ea6\u3092\u7fd2\u6163\u7684\u306b\u98f2\u3080\u300d<\/mark><\/strong>\u3053\u3068\u304c\u826f\u3044\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u4e9c\u925b\u6b20\u4e4f\u3067\u306f\u3001<strong>\u795e\u7d4c\u306e\u708e\u75c7\u3084\u30b7\u30ca\u30d7\u30b9\u6a5f\u80fd\u969c\u5bb3\u3092\u304d\u305f\u3059<\/strong>\u3053\u3068\u3067\u8a8d\u77e5\u75c7\u306e\u767a\u75c7\u3092\u95a2\u9023\u4ed8\u3051\u308b\u75ab\u5b66\u7684\u30a8\u30d3\u30c7\u30f3\u30b9\u304c\u8a8d\u3081\u3089\u308c\u307e\u3059\u3002<strong>\u300c<mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-vivid-red-color\">\u4e9c\u925b<\/mark>\u306e\u6b20\u4e4f\u3067\u306f\u3001\u8a8d\u77e5\u75c7\u767a\u75c7\u306f\u7d0430\uff05\u5897\u52a0\u300d<\/strong>\u3068\u660e\u3089\u304b\u306b\u9ad8\u307e\u308a\u307e\u3059\u3002\u305d\u306e\u4ed6\u3001\u7814\u7a76\u30ec\u30d9\u30eb\u3067\u30a8\u30d3\u30c7\u30f3\u30b9\u306f\u5f31\u3044\u3082\u306e\u306e\u3001\u8a8d\u77e5\u75c7\u4e88\u9632\u306b\u5f79\u7acb\u3064\u53ef\u80fd\u6027\u304c\u6307\u6458\u3055\u308c\u3066\u3044\u308b\u6804\u990a\u7d20\u304c\u8907\u6570\u3042\u308a\u307e\u3059\u3002\u795e\u7d4c\u306b\u30c0\u30e1\u30fc\u30b8\u3092\u4e0e\u3048\u308b<strong>\u30db\u30e2\u30b7\u30b9\u30c6\u30a4\u30f3\u306e\u84c4\u7a4d\u3092\u9632\u304e<\/strong>\u3001\u4f4e\u4e0b\u3057\u305f\u8a8d\u77e5\u6a5f\u80fd\u3092\u6539\u5584\u3059\u308b\u53ef\u80fd\u6027\u304c\u793a\u5506\u3055\u308c\u3066\u3044\u308b\u306e\u306f\u3001<strong><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-vivid-red-color\">\u30d3\u30bf\u30df\u30f3B2\u3001\u30d3\u30bf\u30df\u30f3B12\u3001\u8449\u9178<\/mark><\/strong>\u3067\u3059\u3002\u6297\u9178\u5316\u4f5c\u7528\u3067\u8133\u306e\u9178\u5316\uff08\u8001\u5316\uff09\u3092\u9632\u304e\u3001\u8a8d\u77e5\u75c7\u306e\u30ea\u30b9\u30af\u4f4e\u6e1b\u304c\u671f\u5f85\u3055\u308c\u3066\u3044\u308b\u306e\u306f\u3001<strong><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-vivid-red-color\">\u30d3\u30bf\u30df\u30f3C\u3001\u30d3\u30bf\u30df\u30f3E<\/mark><\/strong>\u3067\u3059\u3002\u8fd1\u5e74\u6ce8\u76ee\u3055\u308c\u3066\u3044\u308b\u3001\u8a8d\u77e5\u6a5f\u80fd\u306e\u4f4e\u4e0b\u3092\u7de9\u3084\u304b\u306b\u3057\u3001\u8a8d\u77e5\u75c7\u767a\u75c7\u30ea\u30b9\u30af\u4f4e\u6e1b\u3092\u793a\u5506\u3059\u308b\u7814\u7a76\u304c\u3042\u308b\u306e\u306f<strong><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-vivid-red-color\">\u30d3\u30bf\u30df\u30f3D<\/mark><\/strong>\u3067\u3059\u3002\u30d3\u30bf\u30df\u30f3\u306e\u904e\u5270\u6442\u53d6\u306b\u6ce8\u610f\u306f\u5fc5\u8981\u3067\u3059\u304c\u3001\u30de\u30eb\u30c1\u30d3\u30bf\u30df\u30f3\u30df\u30cd\u30e9\u30eb\u30b5\u30d7\u30ea\u306e\u670d\u7528\u306f\u6709\u52b9\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u3002\u307e\u305f\u3001\u30d3\u30bf\u30df\u30f3\u4ee5\u5916\u3067\u91cd\u8981\u306a\u6804\u990a\u7d20\u306f\u3001\u8840\u6db2\u3092\u30b5\u30e9\u30b5\u30e9\u306b\u3057\u8133\u306b\u6804\u990a\u3092\u9001\u308b\u30aa\u30e1\u30ac3\u306e<strong><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-vivid-red-color\">DHA<\/mark><\/strong>\u3001\u30a2\u30df\u30ed\u30a4\u30c9\u03b2\u306e\u84c4\u7a4d\u3092\u6291\u5236\u3059\u308b\u3053\u3068\u304c\u793a\u5506\u3055\u308c\u3066\u3044\u308b<strong><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-vivid-red-color\">\u30dd\u30ea\u30d5\u30a7\u30ce\u30fc\u30eb<\/mark><\/strong>\u3067\u3059\u3002<strong>\u30aa\u30e1\u30ac-3(EPA\u30fbDHA)\u591a\u4fa1\u4e0d\u98fd\u548c\u8102\u80aa\u9178<\/strong>\u306b\u95a2\u3057\u3066\u306f\u8cdb\u5426\u4e21\u8ad6\u3042\u308a\u307e\u3057\u305f\u304c\u3001\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u578b\u8a8d\u77e5\u75c7\u307e\u305f\u306fMCI\u3068\u8a3a\u65ad\u3055\u308c\u305f\u60a3\u8005\u3055\u3093\u306e\u8a8d\u77e5\u6a5f\u80fd\u306b\u53ca\u307c\u3059\u5f71\u97ff\u3092\u660e\u3089\u304b\u306b\u3059\u308b\u305f\u3081\u3001\u30e1\u30bf\u89e3\u6790\u304c\u5b9f\u65bd\u3055\u308c\u3066\u3044\u307e\u3059\u3002Nutrition Reviews\u8a8c2025\u5e7410\u67081\u65e5\u53f7\u306e\u5831\u544a\u306b\u3088\u308c\u3070\u3001<strong>\u30aa\u30e1\u30ac-3\u306f\u3001MCI\u60a3\u8005\u306e\u5168\u691c\u67fbIQ\u3001\u60c5\u5831\u51e6\u7406\u3001\u6570\u5b57\u8a18\u61b6\u30fb\u30ef\u30fc\u30ad\u30f3\u30b0\u30e1\u30e2\u30ea\u30fb\u6ce8\u610f\u529b\u306a\u3069\u306e\u8a8d\u77e5\u6a5f\u80fd\u6539\u5584\u306b\u6709\u610f\u306a\u5f71\u97ff<\/strong>\u3092\u53ca\u307c\u3059\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u4f46\u3057\u3001\u7d75\u306e\u5b8c\u6210\u3084\u914d\u7f6e\u306a\u3069\u4e00\u90e8\u306e\u8a8d\u77e5\u6a5f\u80fd\u9818\u57df\u306b\u5bfe\u3059\u308b\u6709\u52b9\u6027\u306f\u8a8d\u3081\u3089\u308c\u3066\u3044\u307e\u305b\u3093\u3002\u6700\u3082\u91cd\u8981\u306a\u306e\u306f\u3001\u3053\u308c\u3089\u795e\u7d4c\u306e\u5065\u5eb7\u3092\u4fdd\u3064\u6804\u990a\u7d20\u3092\u542b\u3080<strong>\u300c\u30d0\u30e9\u30f3\u30b9\u306e\u53d6\u308c\u305f\u98df\u4e8b\u300d<\/strong>\u3067\u3059\u3002<\/p>\n\n\n\n<p 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